发明名称 |
METHODS AND COMPOSITIONS FOR ANTI-EGFR TREATMENT |
摘要 |
In some embodiments, the present invention provides methods for enhancing the sensitivity of cancer cells to anti-EGFR treatment, wherein the method comprises the introduction of a miR-200 miRNA to the cancer cells. In other embodiments, the present invention provides methods for treating cancer by exposing the cancer cells to an anti-EGFR composition after the above-mentioned enhancement step. In other embodiments, the present invention provides methods for assessing and enhancing the sensitivity of cancer cells to anti- EGFR treatment. In various other embodiments, the present invention provides compositions and expression vectors for practicing the afore-mentioned methods. |
申请公布号 |
WO2011059752(A1) |
申请公布日期 |
2011.05.19 |
申请号 |
WO2010US54514 |
申请日期 |
2010.10.28 |
申请人 |
BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM;ADAM, LIANA;DINNEY, COLIN;MCKONKEY, DAVID |
发明人 |
ADAM, LIANA;DINNEY, COLIN;MCKONKEY, DAVID |
分类号 |
C12N15/113 |
主分类号 |
C12N15/113 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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