发明名称 INJECTABLE COMPOSITION CONTAINING HYDROXYCHLOROQUINE FOR LOCAL ADMINISTRATION FOR TREATING CANCER
摘要 The present invention relates to an injectable composition containing hydroxychloroquine for local administration for treating cancer. An anticancer composition according to the present invention exhibits an IC50 value for sarcoma 180, obtained through an in vitro MTT assay, which is approximately 10 times lower than that of cisplatin, and thus exhibits superior cytotoxic effects. In addition, the anticancer composition according to the present invention not only exhibits dose-dependant effects on solid tumors caused by sarcoma 80 in vivo but also exhibits the effect of an elongated life against ascites tumors caused by sarcoma 80.
申请公布号 WO2010151005(A3) 申请公布日期 2011.05.19
申请号 WO2010KR03938 申请日期 2010.06.18
申请人 YEO, OH-YOUNG 发明人 YEO, OH-YOUNG
分类号 A61K9/08;A61K31/44;A61P35/00 主分类号 A61K9/08
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