发明名称 |
METHODS OF CREATING AN INDEX |
摘要 |
Drug discovery is a complex undertaking facing many challenges, not the least of which is a high attrition rate as many promising candidates prove ineffective or toxic in the clinic owing to a poor understanding of the diseases, and thus the biological systems, they target. Therefore, it is broadly agreed that to increase the productivity of drug discovery one needs a far deeper understanding of the molecular mechanisms of diseases, taking into account the full biological context of the drug target and moving beyond individual genes and proteins. The present methods rely on the use of label-free cellular assays, particularly the DMR index, to systematically display the mode of actions, the toxicity, and the target(s) and pathway(s) of any molecules. |
申请公布号 |
WO2010060022(A3) |
申请公布日期 |
2011.05.19 |
申请号 |
WO2009US65490 |
申请日期 |
2009.11.23 |
申请人 |
CORNING INCORPORATED;FANG, YE;FERRIE, ANN, M.;LAHIRI, JOYDEEP;TRAN, ELIZABETH |
发明人 |
FANG, YE;FERRIE, ANN, M.;LAHIRI, JOYDEEP;TRAN, ELIZABETH |
分类号 |
G06F19/00 |
主分类号 |
G06F19/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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