发明名称 |
TIVOZANIB AND TEMSIROLIMUS IN COMBINATION |
摘要 |
A method of treating a tumor in a human patient is disclosed. The method comprises co-administering to the patient: (a) a dose of 1.5 mg tivozanib per day; and (b) a dose of 25 mg temsirolimus per week. In some embodiments of the invention, the tivozanib is administered on a repeating schedule of one dose per day for three weeks, followed by one week without tivozanib administration. The disclosed method is particularly suitable for treatment of renal cell carcinoma.
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申请公布号 |
CA2780495(A1) |
申请公布日期 |
2011.05.19 |
申请号 |
CA20102780495 |
申请日期 |
2010.11.11 |
申请人 |
AVEO PHARMACEUTICALS, INC. |
发明人 |
BHARGAVA, PANKAJ;ESTEVES, W. BROOKE;RYAN, JOHN L. |
分类号 |
A61K31/4709;A61K31/436;A61P35/00 |
主分类号 |
A61K31/4709 |
代理机构 |
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主权项 |
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地址 |
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