| 发明名称 |
GENETIC MODIFICATION OF SOMATIC CELLS AND USES THEREOF |
| 摘要 |
The production of genetically modified animals, in which the genetic modifications are engineered in somatic cells cultured in vitro by gene targeting, is described. Genetically modified cells may then be used as nuclear donors loci in animal chromosomes which are suitable sites for transgene addition to cells.
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| 申请公布号 |
CA2361943(C) |
申请公布日期 |
2011.05.17 |
| 申请号 |
CA20002361943 |
申请日期 |
2000.03.03 |
| 申请人 |
PPL THERAPEUTICS (SCOTLAND) LIMITED |
发明人 |
COLMAN, ALAN;SCHNIEKE, ANGELIKA ELISABETH;KIND, ALEXANDER JARVIS;AYARES, DAVID LEE;DAI, YIFAN |
| 分类号 |
C12N15/10;A01K67/027;A61K48/00;C12N5/071;C12N15/87;C12N15/873;C12N15/90;H04L12/24 |
主分类号 |
C12N15/10 |
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