发明名称 |
MIKROPARTIKEL ZUR VERABREICHUNG VON NUKLEINSÄUREN |
摘要 |
<p>A preparation of microparticles made up of a polymeric matrix, a nucleic acid expression vector, and a lipid. The polymeric matrix includes one or more synthetic polymers having a solubility in water of less than about 1 mg/1. At least 90 % of the microparticles have a diameter less than about 100 microns. The nucleic acid is either RNA, at least 50 % of which is in the form of closed circles, or circular DNA plasmid molecules, at least 50 % of which are supercoiled.</p> |
申请公布号 |
AT508736(T) |
申请公布日期 |
2011.05.15 |
申请号 |
AT20000919403T |
申请日期 |
2000.03.10 |
申请人 |
EISAI INC. |
发明人 |
LUNSFORD, LYNN;PUTNAM, DAVID;HEDLEY, MARY |
分类号 |
A61K9/16;A61K39/00;A61K39/12;A61K39/205;A61K39/29;A61K48/00;C12N15/88 |
主分类号 |
A61K9/16 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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