摘要 |
<P>PROBLEM TO BE SOLVED: To provide compounds directly or indirectly toxic to actively dividing cells, and useful for treatment of cancer, viral and bacterial infections, vascular restenosis, inflammatory diseases, autoimmune diseases or psoriasis. <P>SOLUTION: There is provided the compounds represented by general formulae (I), (II), (III) and (V) (wherein, each symbol has a special definition) for use in modulating microtube polymerization and in the treatment of related disease states. <P>COPYRIGHT: (C)2011,JPO&INPIT |