DIAGNOSTIC METHODS FOR DETERMINING PROGNOSIS OF NON-SMALL CELL LUNG CANCER
摘要
The present disclosure provides methods for identifying early stage non-small-cell lung cancer (NSCLC) patients who will have an unfavorable prognosis for the recurrence of lung cancer after surgical resection. The methods are based in part on the discovery of chromosomal copy number abnormalities that can be used for prognostic classification. The methods preferably use fluorescence in situ hybridization with fluorescently labeled nucleic acid probes to hybridize to patient samples to quantify the chromosomal copy number of these genetic loci.
申请公布号
WO2011056489(A2)
申请公布日期
2011.05.12
申请号
WO2010US53893
申请日期
2010.10.25
申请人
ABBOTT LABORATORIES;SEMINAROV, DIMITRI;LU, XIN;ZHANG, KE;LESNIEWSKI, RICK, R.;COON, JOHN, S.
发明人
SEMINAROV, DIMITRI;LU, XIN;ZHANG, KE;LESNIEWSKI, RICK, R.;COON, JOHN, S.