发明名称 5-HYDROXYPYRIMIDINE-4-CARBOXAMIDE COMPOUND
摘要 The present invention provides compounds which promote erythropoietin production. Compounds represented by the following general formula (1) or pharmacologically acceptable salts thereof are provided: [wherein, R1 represents a group —X-Q1, X-Q1-Y-Q2 or X-Q1-Y-Q2-Z-Q3, X represents a single bond, —CH2— or the like, Q1 represents a monocyclic or bicyclic heterocyclic group which may have substituent(s), Y represents a single bond, —CH2—, or the like, Q2 represents a monocyclic or bicyclic hydrocarbon ring group which may have substituent(s) or a monocyclic or bicyclic heterocyclic group which may have substituent(s), Z represents a single bond, —CR11R12— or the like, R11 and R12 each independently represents a hydrogen atom, a halogen atom or the like, Q3 represents a phenyl group which may have substituent(s), a C3-C7 cycloalkyl group which may have substituent(s), a C3-C7 cycloalkenyl group which may have substituent(s) or a monocyclic or bicyclic heterocyclic group which may have substituent(s), R2 represents a C1-C3 alkyl group or the like, and R3 represents a hydrogen atom or a methyl group].
申请公布号 US2011112103(A1) 申请公布日期 2011.05.12
申请号 US20090988947 申请日期 2009.04.21
申请人 DAIICHI SANKYO COMPANY, LIMITED 发明人 KURIBAYASHI TAKESHI;KUBOTA HIDEKI;FUKUDA TAKESHI;TAKANO RIEKO;TSUJI TAKASHI;SASAKI KOJI;TANAKA NAOKI
分类号 A61K31/513;A61P7/06;C07D401/06;C07D401/10;C07D401/14;C07D403/14;C07D405/06;C07D405/14;C07D409/14;C07D413/14;C07D417/14 主分类号 A61K31/513
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