发明名称 PHARMACEUTICAL COMPOSITION FOR PREVENTING AND TREATING CANCER COMPRISING BENZOHETEROCYCLE DERIVATIVES OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF AS AN ACTIVE INGREDIENT
摘要 PURPOSE: A composition containing benzoheterocycle derivatives for preventing and treating cancer is provided to suppress cancer or tumor by inhibiting interaction of KRS and 67LR. CONSTITUTION: A pharmaceutical composition for preventing or treating cancer contains benzoheterocycle derivative of chemical formula 1 or pharmaceutically acceptable salt thereof as an active ingredient. In chemical formula 1, A is O, NH, or S; X is C or N; and R1 is hydrogen, non-substituted or halogen-substituted alkyl, alkoxy, halogen, nitro, or amine. The cancer is colon cancer, lung cancer, liver cancer, gastric cancer, bladder cancer, uterine cancer, brain cancer, or melanoma.
申请公布号 KR20110049364(A) 申请公布日期 2011.05.12
申请号 KR20090106350 申请日期 2009.11.05
申请人 SNU R&DB FOUNDATION 发明人 KIM, SUNG HOON;CHOI, JIN WOO;LEE, JIN YOUNG;KIM, DAE GYU;HAN, GYOON HEE;YANG, JEE SUN;LEE, CHUL HO
分类号 A61K31/4184;A61K31/423;A61K31/428;A61P35/00 主分类号 A61K31/4184
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