发明名称 |
Attenuated mycobacteria as vectors for gene delivery to mammalian cells |
摘要 |
Provided are mycobacteria comprising a recombinant gene operably liked to a mammalian promoter that directs expression of the recombinant gene from a mammalian cell. Also provided are mammalian cells comprising the above mycobacteria. Additionally provided are mycobacterial plasmids capable of replication in a mycobacterium. Further provided are methods of expressing a recombinant gene in a mammalian cell.
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申请公布号 |
US7939089(B2) |
申请公布日期 |
2011.05.10 |
申请号 |
US20060794372 |
申请日期 |
2006.01.12 |
申请人 |
ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY |
发明人 |
JACOBS, JR. WILLIAM R.;FENNELLY GLENN J. |
分类号 |
A61K39/40;A61K39/00;A61K39/02 |
主分类号 |
A61K39/40 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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