USE OF URINARY NGAL TO DIAGNOSE SEPSIS IN VERY LOW BIRTH WEIGHT INFANTS

摘要

Methods for diagnosis of sepsis very low birth weight (VLBW) infants are disclosed. The diagnostic methods for sepsis are based on determining whether a bodily fluid sample, such as a urine sample, contains an amount of neutrophil gelatinase-associated lipocalin (NGAL) protein that exceeds or is less than a certain threshold level, or that falls within a certain range. The present invention also provides methods for monitoring the progression of sepsis, methods for monitoring sepsis treatment, methods of distinguishing between true-positive and false culture -positive sepsis, and kits for diagnosing sepsis in VLBW infants.