发明名称 |
Process for preparation of inclusion compounds between a non-steroidal anti-inflammatory drug and betacyclodextrin by microwave treatment |
摘要 |
A process for the preparation of inclusion complexes of a drug (piroxicam or ibuprofen) and a cyclodextrin, characterised in that: a) the drug and cyclodextrin, in the form of finely divided powders, are mixed in the presence of aqueous or hydroalcoholic solutions, ammonia solutions or acid solutions; b) the resulting mixture is treated in a microwave oven; c) the resulting product is dried under vacuum at room temperature or with heating.
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申请公布号 |
US7935685(B2) |
申请公布日期 |
2011.05.03 |
申请号 |
US20020499338 |
申请日期 |
2002.12.17 |
申请人 |
CHIESI FARMACEUTICI S.P.A. |
发明人 |
GIORDANO FERDINANDO;BETTINI RUGGERO |
分类号 |
A01N43/04;A61K31/70;A61K31/715;A61K47/48;C07D279/00;C07D285/00;C07D295/00;C07D419/00;C07D513/00 |
主分类号 |
A01N43/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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