发明名称 METHOD FOR PREDICTING THE RESPONSE TO A TREATMENT WITH A HER DIMERIZATION INHIBITOR
摘要 <p>The invention is related to a method of predicting the response to a treatment with a HER dimerization inhibitor in a patient comprising the steps of assessing a marker gene or a combination of marker genes selected from the group consisting of an epidermal growth factor, a transforming growth factor alpha and a HER2 marker gene or a combination of marker genes comprising an amphiregulin marker gene and a marker gene selected from an epidermal growth factor, a transforming growth factor alpha and a HER2 marker gene in a biological sample from the patient and predicting the response to the treatment with the HER dimerization inhibitor in the patient by evaluating the results of the first step. Further uses and methods wherein these markers are used are disclosed.</p>
申请公布号 SI1915460(T1) 申请公布日期 2011.04.29
申请号 SI20060030946T 申请日期 2006.05.24
申请人 F.HOFFMANN-LA ROCHE AG 发明人 MOECKS JOACHIM;STRAUSS ANDREAS;ZUGMAIER GERHARD
分类号 C12Q1/68;G01N33/574 主分类号 C12Q1/68
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