| 发明名称 |
AZAINDAZOLE COMPOUNDS AND METHODS OF USE |
| 摘要 |
Compounds are provided that act as potent antagonists of the CCR1 receptor, and have in vivo anti-inflammatory activity. The compounds are generally aryl piperazine derivatives and are useful in pharmaceutical compositions, methods for the treatment of CCR1-mediated diseases, and as controls in assays for the identification of competitive CCR1 antagonists. |
| 申请公布号 |
US2011098308(A1) |
申请公布日期 |
2011.04.28 |
| 申请号 |
US20100829312 |
申请日期 |
2010.07.01 |
| 申请人 |
CHEMOCENTRYX, INC. |
发明人 |
ZHANG PENGLIE;PENNELL ANDREW M.K.;WRIGHT JOHN J. KIM;CHEN WEI;LELETI MANMOHAN R.;LI YANDONG;LI LIANFA;XU YUAN;GLEASON MARK M.;ZENG YIBIN;GREENMAN KEVIN LLOYD |
| 分类号 |
A61K31/497;A61P1/00;A61P17/00;A61P19/02;A61P25/00;A61P25/16;A61P25/28;A61P37/08;C07D471/04 |
主分类号 |
A61K31/497 |
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