发明名称 |
COMBINATION OF ANGIOPOIETIN-2 ANTAGONIST AND OF VEGF-A, KDR AND/OR FLT1 ANTAGONIST FOR TREATING CANCER |
摘要 |
The invention relates to agents which possess anti-angiogenic activity and are accordingly useful in methods of treatment of disease states associated with angiogenesis in the animal or human body. More specifically the invention concerns a combination of an antagonist of the biological activity of Angiopoietin-2 and an antagonist of the biological activity of VEGF-A, and/or KDR, and/or Flt1, and uses of such antagonists. |
申请公布号 |
US2011097321(A1) |
申请公布日期 |
2011.04.28 |
申请号 |
US20100890101 |
申请日期 |
2010.09.24 |
申请人 |
ASTRAZENECA AB |
发明人 |
BLAKEY DAVID CHARLES;BROWN JEFFREY LESTER;EMERY STEPHEN CHARLES |
分类号 |
A61K39/395;A61K31/337;A61K31/404;A61K31/4375;A61K31/4412;A61K31/517;A61K31/519;A61K31/704;A61K31/7068;A61P35/00;A61P35/02 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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