发明名称 |
USE OF ID4 FOR DIAGNOSIS AND TREATMENT OF CANCER |
摘要 |
The invention relates to a method of determining whether a human subject is suffering from or at risk for developing pancreatic cancer by determining the methylation level of an ID4 gene promoter or the expression level of an ID4 gene in a biological sample from a human subject. Also disclosed are a method of analyzing the methylation level of an ID4 gene promoter or the expression level of an ID4 gene in a pancreatic cancer cell, and a method of inhibiting the methylation of an ID4 gene promoter or enhancing the expression of an ID4 gene by contacting a pancreatic cancer cell with a compound that decreases the methylation level of an ID4 gene promoter or increases the expression level of an ID4 gene in the cell.
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申请公布号 |
US2011098341(A1) |
申请公布日期 |
2011.04.28 |
申请号 |
US20100978286 |
申请日期 |
2010.12.23 |
申请人 |
HOON DAVE S B;UMETANI NAOYUKI |
发明人 |
HOON DAVE S.B.;UMETANI NAOYUKI |
分类号 |
A61K31/713;A61K31/16;A61K31/706;A61P35/00;C12N5/09 |
主分类号 |
A61K31/713 |
代理机构 |
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地址 |
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