| 摘要 |
PURPOSE: A suspension containing megestrol acetate is provided to ensure excellent phase stability, dispersion, and redispersibility. CONSTITUTION: A suspension for oral administration contains megestrol acetate, 0.3-1.0 w/v% of carbomer, 0.05-0.1 w/v% of surfactant, and 0.1-1.5 w/v% of micronized crospovidone. The surfactant is polysorbate. The suspension of oral administration further contains preservative, buffer agent, sweetener, or flavoring agent. A suspension for oral administration contain 4 w/v% of micronized megestrol acetate, 0.6 w/v% of carbomer, 0.05 w/v% of polysorbate 80, 0.5 w/v% of micronized crospovidone, 0.1 w/v% of sodium benzoate; 0.13 w/v% of sodium citrate, 20 w/v% of white sugar, 0.1 w/v% of orange essence, and remaining amount of water.
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