发明名称 |
MODIFICATION OF MYD88 SPLICING USING MODIFIED OLIGONUCLEOTIDES |
摘要 |
Antisense compounds, compositions and methods are provided for modulating the expression of MyD88. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding MyD88. Methods of using these compounds for modulation of MyD88 expression and for treatment of diseases associated with expression of MyD88 are provided.
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申请公布号 |
US2011092573(A1) |
申请公布日期 |
2011.04.21 |
申请号 |
US20100963303 |
申请日期 |
2010.12.08 |
申请人 |
ISIS PHARMACEUTICALS, INC. |
发明人 |
VICKERS TIMOTHY;DEAN NICHOLAS M. |
分类号 |
A61K31/7088;A61P29/00;A61P37/00;C12N5/07 |
主分类号 |
A61K31/7088 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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