发明名称 NOVEL SALT OF MORPHOLINE DERIVATIVE.
摘要 <p>Disclosed is an acid addition salt of (+)-2-[(inden-7-yloxy)methyl]morpholine (compound A), which is intended to be used as a pharmaceutical agent or an active ingredient for a pharmaceutical agent, and has high storage stability, particularly high stability toward humidity and light.  Also disclosed is a novel crystal of the acid addition salt. An acid addition salt of compound A with an acid selected from benzenesulfonic acid and hydrobromic acid is a compound which can be isolated in the form of a crystal, takes a solid form at room temperature, exhibits hygroscopicity at such a level that there is no problem for use as a pharmaceutical agent or an active ingredient for a pharmaceutical agent, has stability toward humidity and light, and is therefore extremely useful as a pharmaceutical agent or an active ingredient for a pharmaceutical agent.</p>
申请公布号 MX2011002728(A) 申请公布日期 2011.04.21
申请号 MX20110002728 申请日期 2009.09.10
申请人 ASTELLAS PHARMA, INC. 发明人 KENICHIROU SAKAMOTO;RYO MIZOGUCHI;KAZUMI KIKUCHI;AKIO KURODA;KAZUHIRO TAKEGUCHI
分类号 C07D265/30 主分类号 C07D265/30
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