摘要 |
<P>PROBLEM TO BE SOLVED: To provide a natural ligand for an orphan G-protein coupled receptor FPRL2 and methods of use thereof, and to provide biological functionality of FPRL2 polypeptide in antibodies prepared against FPRL2. <P>SOLUTION: There are provided methods, reagents and kits for detecting of formyl peptide receptor like-2 (FPRL2) polypeptide activity in a sample and identifying agents which modulate polypeptide activity. Antibodies prepared against FPRL2 are also provided. Substances for preventing, treating and/or alleviating diseases or disorders featured by dysregulation of FPRL2 polypeptide signalling are also provided. <P>COPYRIGHT: (C)2011,JPO&INPIT |