METHOD OF TREATING ULCEROUS DISEASE OF DUODENUM IN CHILDREN, ASSOCIATED WITH FUNGUS OF GENUS Candida

摘要

FIELD: medicine. ^ SUBSTANCE: invention relates to medicine, namely to gastroenterology, and can be applied for treatment of duodenum ulcerous disease in children (UDD). For this purpose in complex therapy included is fluconazole (diflucan). Doses and regime of fluconazole introduction are determined depending on the level of circulating candidal antigen in blood serum. At high level of candidal antigenemia (10-4/10-5 mg/ml) medication is administered in form of intravenous injections in dose 5 mg/kg 1 time per day during 3 days, then 7 days inside in dose 3 mg/kg, and after that 1 time per week once during a month in dose 150 mg. At moderate level of candidal antigenemia (10-6 /10-7 mg/ml) flucanazole is administered inside by 5 mg/kg during 7 days, then 1 time per week in dose 150 mg during a month. At low level of candidal antigen in blood serum (10-8 /10-9 mg/ml) medication is taken inside in dose of 3 mg/kg during 7 days, then once in dose 150 mg. ^ EFFECT: method makes it possible to reduce level of circulating candidal antigen in blood serum of patients with any level of candidal antigenemia. ^ 3 ex