发明名称 |
Method of growing bacteria to deliver bioactive compounds to the intestine of ruminants |
摘要 |
Methods for increasing the resistance to rumen inactivation of a cultured Gram positive bacteria strain useful for gastrointestinal delivery of bioactive compounds to ruminants, which includes the steps of growing a culture of the bacteria strain through at least one passage in a growth medium containing an amount of lysozyme effective to induce the growth of bacterial cell walls resistant to protozoal predation; and recovering the bacteria strain from the lysozyme-containing medium. Rumen-bypass feed supplements produced by the inventive method are also disclosed, as well as methods for supplementing the diet of a ruminant with the rumen bypass feed supplements and an in vitro method for evaluating the resistance of Gram positive bacteria strains to rumen inactivation in vivo. |
申请公布号 |
EP2311937(A1) |
申请公布日期 |
2011.04.20 |
申请号 |
EP20100012875 |
申请日期 |
2005.12.06 |
申请人 |
SAGE BIOSCIENCES INC.;RODE, LYLE M.;NEWBOLD, JAMES C. |
发明人 |
RODE, LYLE M.;NEWBOLD, JAMES C. |
分类号 |
C12N1/20;A23K1/16;A23K1/18;C12N1/36;C12Q1/04;C12R1/15 |
主分类号 |
C12N1/20 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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