COMPOSITION COMPRISING ISOLATED FROM CASSIA TORA OR CASSIA OBTUSIFOLIA OR FOR THE PREVENTION AND TREATMENT OF COGNITIVE DYSFUNCTION DISORDER

摘要

PURPOSE: A composition for treating dementia and amnesia is provided to suppress beta-secretase and to be used as a pharmaceutical composition and health food. CONSTITUTION: A pharmaceutical composition for preventing and treating cognitive disorder contains a compound of general formula I as an active ingredient, isolated from Cassia obtusifolia or Cassia tora. The compound is gluco-obtusifolin, gluco-aurantio-obtusin, alaternin, or chrysophanoltriglucoside. The pharmaceutical composition for preventing and treating cognitive disorder contains a compound of general formula II isolated from Cassia obtusifolia or Cassia tora.