发明名称 |
HYPOGLYCEMIC AGENT IN NON-INSULIN-DEPENDENT DIABETES MELLITUS |
摘要 |
FIELD: medicine, pharmaceutics. ^ SUBSTANCE: offered is the application of hyaluronidase immobilised by electron-beam synthesis nanotechnology as a hypoglycemic agent effective in non-insulin-dependent diabetes mellitus. The mechanism of action is supposed to be modification of the properties of hyaluronic acid of cell glycocalyx and receptors to insulin It is accompanied by higher ligand sensitivity. ^ EFFECT: in non-insulin-dependent hyperglycemia, immobilised hyaluronidase caused peripheral blood sugar level decreasing by 41,9 %; insulin concentration has been decreasing statistically significantly. ^ 2 tbl |
申请公布号 |
RU2416427(C1) |
申请公布日期 |
2011.04.20 |
申请号 |
RU20090146369 |
申请日期 |
2009.12.14 |
申请人 |
OBSHCHESTVO S OGRANICHENNOJ OTVETSTVENNOST'JU "SAENTIFIK F'JUCHER MENEDZHMENT" |
发明人 |
ARTAMONOV ANDREJ VLADIMIROVICH;BEKAREV ANDREJ ALEKSANDROVICH;VERESHCHAGIN EVGENIJ IVANOVICH;DYGAJ ALEKSANDR MIKHAJLOVICH;ZHDANOV VADIM VADIMOVICH;ZJUZ'KOV GLEB NIKOLAEVICH;UDUT VLADIMIR VASIL'EVICH |
分类号 |
A61K38/47;A61P3/10;B82B3/00 |
主分类号 |
A61K38/47 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|