发明名称 |
USE OF TOLL-LIKE RECEPTOR AND AGONIST FOR TREATING CANCER |
摘要 |
<p>The present invention is directed to methods and agents used for treating cancer or infectious diseases by providing toll-like receptors such as toll-like receptor 5 (TLR-5) in combination with providing a toll-like receptor agonists such as flagellin resulting in a cis and in-trans effect that recruits cells involved in both the innate (cis effect) and adaptive (trans effect) immune response to specifically kill cancer cells and cells infected with a pathogen via the NF-?B apoptosis pathway.</p> |
申请公布号 |
CA2777198(A1) |
申请公布日期 |
2011.04.14 |
申请号 |
CA20102777198 |
申请日期 |
2010.10.06 |
申请人 |
PANACELA LABS, INC.;ROSWELL PARK CANCER INSTITUTE |
发明人 |
GUDKOV, ANDREI V. |
分类号 |
C12N15/63;A61K31/59;A61K38/17;A61K38/19;A61K38/22;A61K38/27;A61P31/00;A61P35/00;C07K14/195;C07K14/705;C12N15/12;C12N15/31;C12N15/85 |
主分类号 |
C12N15/63 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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