发明名称 |
A CYTOLYTIC RTX-TOXIN FROM GALLIBACTERIUM ANATIS |
摘要 |
The present invention relates to the field of animal health and in particular the causative agent of a new bacterial poultry disease caused by Gallibacteruim spp, including Gallibacterium anatis, Gallibacterium genomospecies 1 and Gallibacterium genomospecies 2. The invention provides a novel RTX toxin from said Gallibacterium species, the novel toxin being named GtxA (Gallibacterium toxin). In addition the invention provides the amino acid and nucleotide sequences of GtxA, a vaccine comprising inactivated toxoid or fragments of the toxoid as well as methods of immunizing birds to prevent said disease and to methods of diagnosing a Gallibacterium anatis infection in birds.
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申请公布号 |
CA2774734(A1) |
申请公布日期 |
2011.04.14 |
申请号 |
CA20102774734 |
申请日期 |
2010.10.07 |
申请人 |
KOEBENHAVNS UNIVERSITET (UNIVERSITY OF COPENHAGEN) |
发明人 |
BOJESEN, ANDERS MIKI;KRISTENSEN, BODIL MARIE |
分类号 |
C07K14/285;A61K39/102;C07K16/12;C12N15/09;C12Q1/68;G01N33/569 |
主分类号 |
C07K14/285 |
代理机构 |
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地址 |
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