发明名称 |
TABLET QUICKLY DISINTEGRATING IN THE ORAL CAVITY AND METHOD FOR PRODUCING THE SAME |
摘要 |
<p>The present invention relates to a tablet which is rapidly disintegrated in an oral cavity containing an active ingredient at a high content and a production method thereof. That is, the present invention provides a tablet which is rapidly disintegrated in an oral cavity containing an active ingredient in not less than 25% of the total weight, having a disintegration time of within 40 seconds and an absolute hardness of 1.8 N/mm 2 or more, which is obtained by granulating a powder containing an active ingredient with a binding solution containing mannitol and corn-derived pregelatinized starch, mixing the resulting granules with at least one kind of a disintegrant selected from cornstarch, hydroxypropylstarch, carmellose and crospovidone, and compression molding the mixture.</p> |
申请公布号 |
EP2308511(A1) |
申请公布日期 |
2011.04.13 |
申请号 |
EP20090762502 |
申请日期 |
2009.06.10 |
申请人 |
DAINIPPON SUMITOMO PHARMA CO., LTD. |
发明人 |
FUKUSHIMA, TORU;SHIMIZU, TAKASHI;YOSHIDA, TERUKO |
分类号 |
A61K47/10;A61K9/26;A61K31/198;A61K47/32;A61K47/36;A61P25/16 |
主分类号 |
A61K47/10 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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