| 摘要 |
FIELD: medicine. ^ SUBSTANCE: substance of the invention involves a method of detecting an antibody in a sample being tested containing a body fluid of a specified mammal where said antibody is a biological marker of a disease state or propensity for a disease where the method involves (a) contacting said sample being tested with a set of various amounts of an antigen specific to said antibody, (b) evaluating specific binding of said antibody and said antigen, (c) drawing a diagram or calculating a curve of said specific binding to the amount of the antigen for each amount of the antigen used at the stage (a), and (d) stating the presence or absence of said disease state or propensity for the disease by the specific binding of said antibody and said antigen for each individual antigen concentration used where the presence of said disease state or propensy for the disease is detected by screening a titration curve starting with the stage (c) for observing an S-shaped or sigmoid curve. ^ EFFECT: higher sensitivity of the diagnostic technique. ^ 23 cl, 7 ex, 6 tbl, 15 dwg |
