发明名称 |
METHODS OF ACTIVATING NKT CELLS |
摘要 |
Provided are methods of activating an NKT cell which include a step of contacting the NKT cell with a sufficient amount of isoglobotrihexosylceramide (iGb3) to induce secretion of a cytokine from the NKT cell, stimulate proliferation of the NKT cell or upregulate expression of a cell surface marker on the NKT cell. Methods of activating an NKT cell population in a subject are also provided.
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申请公布号 |
US2011082106(A1) |
申请公布日期 |
2011.04.07 |
申请号 |
US20100901971 |
申请日期 |
2010.10.11 |
申请人 |
THE UNIVERSITY OF CHICAGO;BRIGHAM YOUNG UNIVERSITY;THE SCRIPPS RESEARCH INSTITUTE |
发明人 |
BENDELAC ALBERT;ZHOU DAPENG;TEYTON LUC;SAVAGE PAUL |
分类号 |
A61K31/702;A61P31/00;A61P35/00;A61P37/06;C12N5/0783 |
主分类号 |
A61K31/702 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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