发明名称 |
SUBSTRATES FOR GLYCOGEN SYNTHASE KINASE 3 ENZYMES AND METHODS OF USE |
摘要 |
Methods and compositions for glycogen synthase kinase 3 assays continue to be required for detection of glycogen synthase 3 kinase, assessment of glycogen synthase 3 kinase activity and identification of modulators of glycogen synthase 3 kinase. Methods and compositions for glycogen synthase kinase 3 assays are provided herein based on the discovery of a previously unknown interaction between glycogen synthase 3 kinase and eukaryotic translation initiation factor 4E-binding protein 1 which serves as a substrate for glycogen synthase kinase 3-alpha and glycogen synthase kinase 3-beta.
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申请公布号 |
US2011081659(A1) |
申请公布日期 |
2011.04.07 |
申请号 |
US20100892615 |
申请日期 |
2010.09.28 |
申请人 |
RODRIGUEZ-SUAREZ ROBERTO J;BEAUDET LUCILLE;CARON MIREILLE |
发明人 |
RODRIGUEZ-SUAREZ ROBERTO J.;BEAUDET LUCILLE;CARON MIREILLE |
分类号 |
G01N33/573;C07K14/00;C12Q1/48 |
主分类号 |
G01N33/573 |
代理机构 |
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地址 |
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