发明名称 |
INTRACELLULAR VIRAL VECTOR DELIVERY METHOD EMPLOYING IRON ION/VIRAL VECTOR COMPOSITE |
摘要 |
The present invention relates to an intracellular viral vector delivery method employing an iron ion/viral vector composite. The iron ion/viral vector composite according to the present invention is not dependent on the expression of CAR and so improves the efficiency of delivery of viral vectors and gene expression in cells of diverse types, and has an outstanding virus-neutralizing antibody escape performance, exhibits little cytotoxicity and is outstandingly stable even when subjected to iron ion processing at low concentration, and hence can be used to advantage in recombinant viral vaccine compositions. |
申请公布号 |
WO2011040738(A2) |
申请公布日期 |
2011.04.07 |
申请号 |
WO2010KR06577 |
申请日期 |
2010.09.28 |
申请人 |
POSTECH ACADEMY-INDUSTRY FOUNDATION;BIOD CO., LTD.;SUNG, YOUNG CHUL;PARK, SANG HOON;PARK, KI SEOK |
发明人 |
SUNG, YOUNG CHUL;PARK, SANG HOON;PARK, KI SEOK |
分类号 |
C12N15/83;C12N5/10;C12N15/87 |
主分类号 |
C12N15/83 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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