IMPROVED PROCESS FOR THE PREPARATION OF PURE RABEPRAZOLE
摘要
The present invention relates to a process for the preparation of pure rabeprazole base using the solvent mixture for the extraction steps and this invention further relates to the process for the preparation of amorphous rabeprazole sodium using pure rabeprazole base in the presence of aqueous NaOH and water miscible solvent and adding an anti-solvent.
申请公布号
WO2008155780(A3)
申请公布日期
2011.03.31
申请号
WO2008IN00388
申请日期
2008.06.19
申请人
MATRIX LABORATORIES LTD;TYAGI, OM, DUTT;RAY, PURNA, CHANDRA;SETHI, MADHURESH, KUMAR;CHAVHAN, BHAUSAHEB
发明人
TYAGI, OM, DUTT;RAY, PURNA, CHANDRA;SETHI, MADHURESH, KUMAR;CHAVHAN, BHAUSAHEB