| 发明名称 |
Cripto blocking antibodies and uses thereof |
| 摘要 |
Disclosed is an antibody that specifically binds to an epitope comprised in the cysteine-rich domain of Cripto spanning amino acid residues 114-150 of SEQ ID NO: 1 or SEQ ID NO:2. The antibody can be used for decreasing tumor growth.
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| 申请公布号 |
NZ578287(A) |
申请公布日期 |
2011.03.31 |
| 申请号 |
NZ20020578287 |
申请日期 |
2002.04.17 |
| 申请人 |
BIOGEN IDEC MA INC. |
发明人 |
SANICOLA-NADEL, MICHELE;WILLIAMS, KEVIN;SCHIFFER, SUSAN GAIL;RAYHORN, PAUL |
| 分类号 |
A61K39/395;A61P35/00;C07K16/00;C07K16/18;C07K16/28;C07K16/30;C07K16/46;C07K19/00;C12N15/09 |
主分类号 |
A61K39/395 |
| 代理机构 |
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代理人 |
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