发明名称 |
NOVEL 17 BETA LUPANE DERIVATIVES |
摘要 |
The invention relates to 17&bgr; lupane derivatives of formula (I): wherein R1 and X are as defined herein, and pharmaceutically acceptable salts and solvates thereof. These compounds exhibit significant anti-HIV activity. Thus, the invention also relates to methods for prevention or treatment of HIV infection by administering therapeutically effective amounts of a compound of formula (I), or a pharmaceutically acceptable salt or solvate thereof to a subject in need of such treatment.
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申请公布号 |
US2011077251(A1) |
申请公布日期 |
2011.03.31 |
申请号 |
US20100856848 |
申请日期 |
2010.08.16 |
申请人 |
MOINET CHRISTOPHE;LIU BINGCAN;HALAB LILIANE;TURCOTTE NATHALIE;DENIS REAL;POISSON CARL;NGUYEN-BA PAUL;BUBENIK MONICA;KONG LAVAL CHAN CHUN |
发明人 |
MOINET CHRISTOPHE;LIU BINGCAN;HALAB LILIANE;TURCOTTE NATHALIE;DENIS REAL;POISSON CARL;NGUYEN-BA PAUL;BUBENIK MONICA;KONG LAVAL CHAN CHUN |
分类号 |
A61K31/5375;A61K31/215;A61K31/351;A61K31/40;A61K31/415;A61K31/4245;A61K31/426;A61K31/4409;A61K31/4453;A61K31/495;A61P31/18;C07C69/34;C07C69/74;C07C271/24;C07D207/04;C07D211/32;C07D211/60;C07D213/75;C07D231/14;C07D271/113;C07D277/46;C07D295/195;C07D309/06 |
主分类号 |
A61K31/5375 |
代理机构 |
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代理人 |
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地址 |
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