Hyperblebbing Shigella strains are generated by disrupting one or more components of the Tol-Pal system. The blebs from these strains are useful immunogens for vaccination. The individual proteins found in these blebs can also be used as immunogens.
申请公布号
WO2011036564(A2)
申请公布日期
2011.03.31
申请号
WO2010IB02582
申请日期
2010.09.28
申请人
NOVARTIS VACCINES INSTITUTE FOR GLOBAL HEALTH SRL;GERKE, CHRISTIANE;BERLANDA SCORZA, FRANCESCO;SAUL, ALLAN;MAGGIORE, LUANA
