发明名称 |
SUBSTITUTED AMIDE COMPOUND |
摘要 |
<p>Disclosed is a substituted amide represented by formula (I), which is useful as an active ingredient of a pharmaceutical composition, especially as an active ingredient of a pharmaceutical composition for the treatment of diseases that are induced by lysophosphatidic acid (LPA). (In the formula, A represents an optionally substituted aryl group or the like; B represents an optionally substituted aromatic five-membered heterocyclic group; X represents a single bond or a -(CRX1RX2)n- group; n represents 1, 2, 3 or 4; RX1 and RX2 each represents a hydrogen atom or the like; Y1-Y5 each represents a CRY group or N; RY represents a hydrogen atom or the like; R1 and R2 each represents a hydrogen atom or the like; m represents 1, 2 or 3; R3 represents a hydrogen atom or the like; and R4 represents an optionally substituted lower alkyl group or the like.)</p> |
申请公布号 |
WO2011037192(A1) |
申请公布日期 |
2011.03.31 |
申请号 |
WO2010JP66572 |
申请日期 |
2010.09.24 |
申请人 |
ASTELLAS PHARMA INC.;KAWAMINAMI EIJI;TAKAHASHI TATSUHISA;KANAYAMA TAKATOSHI;FUKUDA YUTA;KAIZAWA HIROYUKI;KONDOH YUTAKA;SEO RYUSHI;KURAMOTO KAZUYUKI;TAKE KAZUHIKO;SAKAMOTO KAZUYUKI |
发明人 |
KAWAMINAMI EIJI;TAKAHASHI TATSUHISA;KANAYAMA TAKATOSHI;FUKUDA YUTA;KAIZAWA HIROYUKI;KONDOH YUTAKA;SEO RYUSHI;KURAMOTO KAZUYUKI;TAKE KAZUHIKO;SAKAMOTO KAZUYUKI |
分类号 |
C07D207/34;A61K31/341;A61K31/381;A61K31/401;A61K31/415;A61K31/42;A61K31/426;A61K31/427;A61K31/433;A61K31/44;A61K31/4439;A61K31/454;A61K31/4709;A61K31/496;A61K31/4965;A61K31/505;A61K31/506;A61K31/5377;A61K31/538;A61K31/541;A61P9/00;A61P13/00;A61P25/00;A61P29/00;A61P35/00;A61P43/00;C07D213/81;C07D231/12;C07D239/28;C07D241/24;C07D261/18;C07D263/32;C07D263/34;C07D277/20;C07D277/30;C07D277/56;C07D307/68;C07D333/24;C07D333/28;C07D333/38;C07D417/12 |
主分类号 |
C07D207/34 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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