Systems for ex-vivo organ care

摘要

An organ care system is disclosed. The organ care system comprises a portable multiple use module including a portable chassis and a pump driver; and a single use disposable module. The single use disposable module includes a disposable chassis sized and shaped for interlocking the single use module with the multiple use module for electro-mechanical interoperation with the multiple use module. A perfusion circuit is provided for circulating perfusion fluid. The perfusion circuit includes a pump interface having a housing in fluid tight interconnection with a surface that is movable with respect to the housing to translate pumping force from the pump driver to the perfusion fluid. An organ chamber assembly is mounted to the disposable chassis for containing a heart during perfusion and includes a first interface for connecting the perfusion circuit to an aorta of the heart and a second interface for connecting the perfusion circuit to a pulmonary vein of the heart. The pump driver separably aligns with the pump interface upon interlocking the single use disposable module with the portable multiple use module.