| 摘要 |
FIELD: medicine, pharmaceutics. ^ SUBSTANCE: invention refers to new spirooxyindole derivatives of formula (I): where k, j, Q, R1, R2a, R2b, R2c, R2d, R3a, R3b, R3c and R3d have the values specified in the patent claim, in the form of their stereoisomer, enantiomer, tautomer or their mixtures or their pharmaceutically acceptable salt. Also, there are discovered pharmaceutical compositions involving such compounds, and methods for preparation and application of the compounds. ^ EFFECT: preparation of the compounds which can be used in treatment and/or prevention of sodium channel mediated diseases or conditions, such as pain. ^ 55 cl, 13 dwg, 10 tbl, 377 ex |
