Provided herein are compounds and methods for use in preventing or treating a viral infection mediated by a virus comprising an IRES-containing RNA molecule or cancer related to an increase or decrease in IRES-mediated translation of an RNA molecule. Also provided are methods of inhibiting or promoting IRES-mediated translation. Also provided are methods of screening for an agent that inhibits IRES-mediated translation.
申请公布号
WO2010111653(A3)
申请公布日期
2011.03.24
申请号
WO2010US28917
申请日期
2010.03.26
申请人
THE UAB RESEARCH FOUNDATION;DISCOVERYBIOMED, INC.;THOMPSON, SUNNIE R.;SCHWIEBERT, ERIK MILLS;STREIFF, JOHN H.
发明人
THOMPSON, SUNNIE R.;SCHWIEBERT, ERIK MILLS;STREIFF, JOHN H.
