METHOD FOR REFINING 3-AMINO-1-tert-BUTOXYCARBONYLPIPERIDINE

摘要

3-amino-1-tert-butoxycarbonylpiperidine can be refined by an industrially advantageous method by means of a 3-amino-1-tert-butoxycarbonylpiperidine refining method including: a step wherein a citrate of 3-amino-1-tert-butoxycarbonylpiperidine is prepared by reacting 3-amino-1-tert-butoxycarbonylpiperidine and citric acid in methanol, ethanol, 2-propanol, or a mixed solvent thereof, and said citrate that has crystallized is acquired; and a step wherein the acquired citrate is treated with a base, and the freed 3-amino-1-tert-butoxycarbonylpiperidine is isolated.