AN ENZYMATICALLY CATALYZED METHOD OF PREPARING MONO-ACYLATED POLYOLS
摘要
The present invention relates to a biocatalytic method of preparing a mono-acylated polyol catalyzed by triacylglycerol lipase mutants, as for example derived from Candida antarctica lipase B (CALB); a biocatalytic method of enantioselectively preparing an asymmetric mono-acylated polyol, catalyzed by the same enzyme mutants; as well as the use of a mutated triacylglycerol lipase in a method of preparing mono-acylated polyols. The invention also provides novel mutants, coding sequences thereof, and recombinant microorganisms carrying said coding sequences.
申请公布号
WO2011033039(A1)
申请公布日期
2011.03.24
申请号
WO2010EP63645
申请日期
2010.09.16
申请人
BASF SE;HAUER, BERNHARD;KVARNSTROEM BRANNEBY, CECILIA;HULT, KARL;MAGNUSSON, ANDERS;HAMBERG, ANDERS
发明人
HAUER, BERNHARD;KVARNSTROEM BRANNEBY, CECILIA;HULT, KARL;MAGNUSSON, ANDERS;HAMBERG, ANDERS