发明名称 ASSISTED ENZYME REPLACEMENT THERAPY
摘要 Reagents and methods useful for the synthesis of conjugates comprising guanidinylated cyclic acetals are provided. Also provided are methods for increasing the cellular uptake of various therapeutic compounds and treatment modalities using these conjugates.
申请公布号 WO2011034951(A2) 申请公布日期 2011.03.24
申请号 WO2010US48968 申请日期 2010.09.15
申请人 THE REGENTS OF THE UNIVERSITY OF CALIFORNIA;ESKO, JEFFREY D.;TOR, YITZHAK 发明人 ESKO, JEFFREY D.;TOR, YITZHAK
分类号 A61K31/7036;A61K31/352;A61K31/70;A61K31/7048;A61K38/43;A61P3/00;A61P43/00 主分类号 A61K31/7036
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