发明名称 |
N-terminally truncated HER-2/NEU protein as a cancerprognostic indicator |
摘要 |
There is disclosed an initial identification of an N-terminally truncated HER-2/neu product. This product is a 95kDa polypeptide having in vitro kinase activity (as determined by western blotting). Moreover, immunoprecipitations using domain specific antibodies was able to utilize this specific polypeptide from intracellular fragments as a diagnostic and prognostic indicator of adenomacarcinomas without the severe dilution effects encountered by measuring ECD.
|
申请公布号 |
EP2299272(A2) |
申请公布日期 |
2011.03.23 |
申请号 |
EP20100012117 |
申请日期 |
1999.11.13 |
申请人 |
OREGON HEALTH SCIENCES UNIVERSITY |
发明人 |
CLINTON, GAIL M. |
分类号 |
G01N33/53;G01N33/574;A61K31/198;A61K38/00;A61K39/395;A61P35/00;C12Q1/48;G01N33/15;G01N33/50;G01N33/566;G01N33/577 |
主分类号 |
G01N33/53 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|