| 发明名称 |
Immunoglobulin Variants Outside the Fc Region |
| 摘要 |
The present invention relates to antibody variants outside the Fc region that alter binding affinity to one or more effector ligands, methods for their generation, and their therapeutic application. |
| 申请公布号 |
US2011064727(A9) |
申请公布日期 |
2011.03.17 |
| 申请号 |
US20070841530 |
申请日期 |
2007.08.20 |
| 申请人 |
XENCOR, INC. |
发明人 |
LAZAR GREGORY ALAN;KARKI SHER BAHADUR |
| 分类号 |
A61K39/395;A61P43/00;C07K16/00;C07K16/18;C07K16/28;C07K16/32;C07K16/44 |
主分类号 |
A61K39/395 |
| 代理机构 |
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代理人 |
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