摘要 |
The present invention provides methods and compositions for the stimulation of immune responses. Specifically, the present invention provides methods of inducing an immune response against one or a plurality of pathogens (e.g., vaccinia virus, H5N1 influenza virus, Bacillus anthracis, C. botulinum, Y. pestis, Hepatits B, and/or HIV, etc.) in a subject (e.g., a human subject) and compositions useful in such methods (e.g., immunogenic composition comprising nanoemulsion and one or a plurality of pathogens (e.g., inactivated by the nanoemulsion) and/or pathogen products and/or pathogen components). Compositions and methods of the present invention find use in, among other things, clinical (e.g. therapeutic and preventative medicine (e.g., vaccination)) and research applications |
申请人 |
THE REGENTS OF THE UNIVERSITY OF MICHIGAN |
发明人 |
BAKER, JAMES, R., JR.;BIELINSKA, ANNA, U.;MANK, NICHOLAS J.;MAKIDON, PAUL, E.;KNOWLTON, JESSICA, A.;BLANCO, LUZ, P.;CAO, ZHENGYI;SCOTT, ALISON, J.;NIGAVEKAR, SHRADDHA, S. |