发明名称 |
NOVEL 3-AMINOALKYL-1,3-DIHYDRO-2H-INDOL-2-ONE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF |
摘要 |
The present invention relates to novel 3-aminoalkyl-1,3-dihydro-2H-indol-2-one derivatives, to their preparation and to their therapeutic application. The compounds of the present invention correspond to the formula (I): in which the variables are as set forth in the specification. These compounds exhibit a strong affinity and a high selectivity for human arginine-vasopressin (AVP) V1a receptors and some compounds additionally exhibit a strong affinity for AVP V1b receptors.
|
申请公布号 |
US2011059955(A1) |
申请公布日期 |
2011.03.10 |
申请号 |
US20100858976 |
申请日期 |
2010.08.18 |
申请人 |
SANOFI-AVENTIS |
发明人 |
FOULON LOIC;GOULLIEUX LAURENT;POUZET BRIGITTE;SERRADEIL-LE GAL CLAUDINE;VALETTE GERARD |
分类号 |
A61K31/551;A61K31/404;A61K31/454;A61K31/496;A61K31/5377;A61P1/00;A61P9/00;A61P9/12;A61P11/00;A61P25/00;A61P35/00;C07D209/04;C07D401/06;C07D403/02;C07D413/06;C07D471/08 |
主分类号 |
A61K31/551 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|