发明名称 |
HIGH AFFINITY HUMAN ANTIBODIES TO HUMAN PROTEASE-ACTIVATED RECEPTOR-2 |
摘要 |
The present invention provides antibodies that bind to protease-activated receptor-2 (PAR-2) and methods of using same. According to certain embodiments of the invention, the antibodies are fully human antibodies that bind to human PAR-2. The antibodies of the invention are useful, inter alia, for the treatment of diseases and disorders associated with one or more PAR-2 biological activities, including the treatment of pain conditions, inflammatory conditions and gastrointestinal conditions.
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申请公布号 |
US2011059095(A1) |
申请公布日期 |
2011.03.10 |
申请号 |
US20100877133 |
申请日期 |
2010.09.08 |
申请人 |
REGENERON PHARMACEUTICALS, INC. |
发明人 |
MACDONALD LYNN;MURPHY ANDREW J.;PAPADOPOULOS NICHOLAS J.;MORRA MARC R.;SALZLER ROBERT R.;LACROIX-FRALISH MICHAEL L. |
分类号 |
A61K39/395;A61P1/00;A61P1/04;A61P1/18;A61P11/06;A61P17/04;A61P19/02;A61P29/00;A61P35/00;C07K16/28 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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