| 发明名称 |
DETERMINING SENSITIVITY OF CELLS TO B-RAF INHIBITOR TREATMENT BY DETECTING KRAS MUTATION AND RTK EXPRESSION LEVELS |
| 摘要 |
<p>The present invention relates to prognostic methods for identifying tumors that are not susceptible to B-Raf inhibitor treatment by detecting mutations in a K-ras gene or protein or by detecting overexpression of RTKs and/or their ligands. Kits are also disclosed for carrying out the methods.</p> |
| 申请公布号 |
CA2771369(A1) |
申请公布日期 |
2011.03.10 |
| 申请号 |
CA20102771369 |
申请日期 |
2010.08.24 |
| 申请人 |
GENENTECH, INC. |
发明人 |
HATZIVASSILIOU, GEORGIA;MALEK, SHIVA |
| 分类号 |
C12Q1/68;G01N33/48;G01N33/574 |
主分类号 |
C12Q1/68 |
| 代理机构 |
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