| 发明名称 |
3,4-SUBSTITUTED PIPERIDINE DERIVATIVES AS RENIN INHIBITORS |
| 摘要 |
The present invention relates to 3,4-substituted piperidinyl-based renin inhibitor compounds bearing at 4-position oxopyridine and having the formula (I). The invention further relates to pharmaceutical compositions containing said compounds, as well as their use in treating cardiovascular events and renal insufficiency.
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| 申请公布号 |
US2011053940(A1) |
申请公布日期 |
2011.03.03 |
| 申请号 |
US20090990927 |
申请日期 |
2009.05.04 |
| 申请人 |
CHEN AUSTIN CHIH-YU;DUBE DANIEL;FOURNIER PIERRE-ANDRE;GRIMM ERICH L;LACOMBE PATRICK;LALIBERTE SEBASTIEN;MACDONALD DWIGHT;MACKAY D BRUCE;MCKAY DANIEL JAMES;WU TOM YAO-HSIANG;CAMPEAU LOUIS-CHARLES;SCOTT JEREMY PETER;BREMEYER NADINE |
发明人 |
CHEN AUSTIN CHIH-YU;DUBE DANIEL;FOURNIER PIERRE-ANDRE;GRIMM ERICH L.;LACOMBE PATRICK;LALIBERTE SEBASTIEN;MACDONALD DWIGHT;MACKAY D. BRUCE;MCKAY DANIEL JAMES;WU TOM YAO-HSIANG;CAMPEAU LOUIS-CHARLES;SCOTT JEREMY PETER;BREMEYER NADINE |
| 分类号 |
A61K31/4545;A61K31/4709;A61K31/4725;A61K31/5377;A61P9/00;A61P9/10;A61P9/12;A61P11/00;A61P13/12;A61P25/00;A61P27/02;C07D401/04;C07D401/14;C07D413/14 |
主分类号 |
A61K31/4545 |
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